Figure 1
From: Altered effector function of peripheral cytotoxic cells in COPD
Proportion and type of peripheral blood mononuclear cells in HNS (n = 12), smokers (n = 15) and COPD subjects (n = 10). Results show a significant decrease in the proportion of NK (CD56+CD3-) cells (*; p < 0.05) and NKT-like (CD56+CD3+) cells (***; p < 0.001) in COPD subjects compared to HNS. Smokers had a significantly lower proportion of B-cells (***; p < 0.001) compared to the other two groups and a greater proportion of CD4+ T helper cells. Cell types were determined by flow cytometric analysis of monoclonal antibodies. CD19, B cells; CD4, T helper cells; CD8, cytotoxic killer cells; CD56+CD3-, NK cells; CD56+CD3+, NKT-like cells.