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Table 1 Test group 1 particle gradient compared to background after a single actuation of BDP-HFA PMDI: decrease in submicrometric and increase in larger particle number in the presence of ETS.

From: Inhaled steroid/tobacco smoke particle interactions: a new light on steroid resistance

Particle diameter

0.3–1.0 μm

1.1–2.0 μm

2.1–3.0 μm

3.1–4.0 μm

4.1–5.0 μm

> 5.1 μm

Ambient Air

Test # 1

19538 ± 2373

1421 ± 251

632 ± 162

58 ± 45

17 ± 35

12 ± 45

Test # 2

19759 ± 1355

1343 ± 191

504 ± 107

21 ± 46

11 ± 30

30 ± 42

Test # 3

18536 ± 849

1505 ± 178

643 ± 128

38 ± 41

25 ± 30

20 ± 42

Pooled data of 3 tests

19277 ± 2292

1423 ± 249

593 ± 156

39 ± 45

18 ± 32

21 ± 43

ETS

Test # 4

-4430 ± 4895

4523 ± 1186

1968 ± 668

108 ± 67

25 ± 38

9 ± 40

Test # 5

-3941 ± 5193

4655 ± 1228

2039 ± 741

106 ± 72

24 ± 41

16 ± 49

Test # 6

-3389 ± 5481

4546 ± 9367

2412 ± 4375

103 ± 172

40 ± 52

26 ± 38

Pooled data of 3 tests

-3920 ± 5330*

4575 ± 5522*

2140 ± 2584*

106 ± 115*

30 ± 44*

17 ± 43

  1. ETS = Environmental Tobacco Smoke; BDP-HFA pMDI = beclomethasone-hydrofluoralkane pressurized metered dose inhaler; μm = micrometers.
  2. Values are number of particles/liter (mean ± SD).
  3. *P < 0.001 as compared to pooled data in clean air for the same particle diameter.