Table 1 BALF analysis and lung function parameters

Sex, male/female

12/14

9/12

5/9

Age, yr

39 (25–59)**†

50 (34–75)***

28 (21–39)

X-ray stage (0/I/II/III)

0/17/8/1

0/5/9/4 (3 ND)

14/0/0/0

BAL analyses

% recovery

72 (44–82)

67 (44–80)

72 (61–85)

% viability

95 (85–99.6)

95 (82–98.2)

95 (86–98)

Cell concentration (*10⁶/L)

196 (49–588)**

219 (84–746)***

101 (50–167)

Differential cell counts

% macrophages

72 (39.4–91)**

62.2 (37–91)***

87 (65–95)

% lymphocytes

28 (7.6–58)**

34.6 (8.2–61)***

11 (3.8–29)

% neutrophils

0.9 (0–4.8)

1.0 (0–6.0)

1.6 (0.2–4.4)

% eosinophils

0.2 (0–1.8)

0.5 (0.–4.4)

0.5 (0–1.6)

CD4/CD8 ratio

8.7 (2.4–28.4)

7.2 (0.9–46)

ND

HLA-DRB1*0301

20 of 24 (2 ND)

2 of 19 (2 ND)

ND

AV2S3 expansion¹⁾

21 of 26

4 of 19 (2 ND)

ND

Pulmonary function tests

VC (% of ref value)

90 (68–126)

78 (53–133)

ND

FEV1 (% of ref value)

88 (66–122)†

74 (56–131)

ND

DLco (% of ref value)

83 (66–126)

81 (54–106)

ND