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Table 1 Subject demography and descriptive data of variables

From: COPD phenotype description using principal components analysis

Variable Mean (SD)
Age (years) 64.6 (7.6)
Gender (M/F) 80/47
ICS use (yes/no) 73/54
ICS daily dosage (microgrammes)$ 990.4 (695.2)
Smoking pack years 47 (23)
IC (litres) 2.2 (0.6)
FEV1 (% Predicted) 61.2 (15.0)
Reversibility (%) 6.1 (5.7)
BMI 27 (0.5)
FeNO (ppb) 15.9 (13.8–18.3)*
Sputum IL8 (pg/ml) 641.3 (536.5–766.6)*
CRP (mg/ml) 3.1 (2.5–3.8)*
TNFα (pg/ml) 1.6 (1.5–1.8)*
Sputum TCC (×106) 4.8 (3.5–6.2)*
Sputum Neutrophil TCC (×106) 4.2 (2.8–5.5)*
Sputum Eosinophil TCC (×106) 0.2 (0.1–0.3)*
Sputum Neutrophil % 76.9 (73.5–80.3)*
Sputum Eosinophil % 6.2 (3.9–8.6)*
  1. *Geometric mean (95% confidence interval presented for variables that were log transformed.
  2. ICS; inhaled corticosteroid, IC; inspiratory capacity, FEV1; forced expiratory volume in 1 second, BMI; body mass index, FeNO; fractional exhaled nitric oxide, CRP; C-Reactive Protein, TNFα tumour necrosis factor-alpha, TCC; total cell count.
  3. $ Beclomethasone dipropionate equivalent ICS total daily dosage in 73 ICS users