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Table 1 Subject demography and descriptive data of variables

From: COPD phenotype description using principal components analysis

Variable

Mean (SD)

Age (years)

64.6 (7.6)

Gender (M/F)

80/47

ICS use (yes/no)

73/54

ICS daily dosage (microgrammes)$

990.4 (695.2)

Smoking pack years

47 (23)

IC (litres)

2.2 (0.6)

FEV1 (% Predicted)

61.2 (15.0)

Reversibility (%)

6.1 (5.7)

BMI

27 (0.5)

FeNO (ppb)

15.9 (13.8–18.3)*

Sputum IL8 (pg/ml)

641.3 (536.5–766.6)*

CRP (mg/ml)

3.1 (2.5–3.8)*

TNFα (pg/ml)

1.6 (1.5–1.8)*

Sputum TCC (×106)

4.8 (3.5–6.2)*

Sputum Neutrophil TCC (×106)

4.2 (2.8–5.5)*

Sputum Eosinophil TCC (×106)

0.2 (0.1–0.3)*

Sputum Neutrophil %

76.9 (73.5–80.3)*

Sputum Eosinophil %

6.2 (3.9–8.6)*

  1. *Geometric mean (95% confidence interval presented for variables that were log transformed.
  2. ICS; inhaled corticosteroid, IC; inspiratory capacity, FEV1; forced expiratory volume in 1 second, BMI; body mass index, FeNO; fractional exhaled nitric oxide, CRP; C-Reactive Protein, TNFα tumour necrosis factor-alpha, TCC; total cell count.
  3. $ Beclomethasone dipropionate equivalent ICS total daily dosage in 73 ICS users