Figure 2
From: Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough
Expression of TGFβ1 protein in bronchial biopsies. Examples of TGFβ1 expression in biopsies from normal (Panel A) and from chronic cough patients (Panels B and C) patients. There is increased staining for TGFβ in the airway smooth muscle and epithelial cells in the biopsies from chronic cough patients. Negative control where the primary antibody has been replaced by normal rabbit immunoglobulin does not show any staining (not shown). Magnification is ×400 for Panels A and B, ×200 for Panel C. Panel D. Immunostaining intensity for TGFβ1 (grade 0 to 4) in epithelium (EPI) and in airway smooth muscle (ASM) from 10 normal and 16 cough patients. **p < 0.01, *p < 0.05; horizontal bar shows the mean.