Table 5 Sensitivity and specificity of challenge at different cut points for a positive test.
Exercise Positive Cut-Points – % fall from baseline | 10% | 15% | 20% | |
|---|---|---|---|---|
Mannitol | Sensitivity | 58.6 | 69.4 | 78.6 |
n = 372 | Specificity | 65.2 | 62.0 | 60.8 |
Excluding those with challenge > 35 min | Sensitivity | 64.1 | 75.3 | 82.7 |
n = 319 | Specificity | 59.9 | 57.0 | 55.4 |
Methacholine 16 mg/ml | Sensitivity | 55.2 | 67.4 | 80.3 |
n = 375 | Specificity | 68.9 | 66.1 | 65.2 |