Figure 3
Effect of chronic cigarette smoke exposure on the protein levels of inflammatory mediators in bronchoalveolar lavage fluid. Protein levels of inflammatory mediators in the bronchoalveolar lavage fluid of wild type and NK1-R-/- mice upon chronic (24 weeks) exposure to air or cigarette smoke, as measured by ELISA: (A) MIP-3α, (B) KC and (C) TGF-β1. Results are expressed as pg/ml (mean ± SEM). N = 8 animals per group (* p < 0.05). (MIP-3α: Macrophage Inflammatory Protein-3α; KC: mouse interleukin-8; TGF-β1: Transforming Growth Factor-β1).