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Figure 5 | Respiratory Research

Figure 5

From: Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat

Figure 5

IOD average of collagen I and III in the rat lungs. (A) The IOD averages of collagen I of the silica, the silica+Lv-shCD36 and the silica+Lv-shCD36-NC groups were significantly higher than those of the saline control group at three time points. The IOD averages of collagen I of the silica+Lv-shCD36 group were significantly lower than those of the silica and the silica+Lv-shCD36-NC groups. (B) The IOD averages of collagen III of the silica, the silica+Lv-shCD36 and the silica+Lv-shCD36-NC groups were significantly higher than those of the saline control group at three time points. The IOD averages of collagen III of the silica+Lv-shCD36 group were significantly lower than those of the silica and the silica+Lv-shCD36-NC groups. Each bar represents the mean ± SEM. *P < 0.05, as compared to the saline control group;Δ P < 0.05, as compared to the silica group; and # P < 0.05, as compared to the silica+Lv-shCD36-NC group. The data represent the means from experiments done in six rats.

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Respiratory Research

ISSN: 1465-993X

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