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Figure 3 | Respiratory Research

Figure 3

From: Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease

Figure 3

Outline of a Surface Plasmon Resonance (SPR) system utilising a Kretschman-Raether configuration. A system with this configuration facilitates label-free detection of biomolecules that bind in real-time. Biomolecules within the sample bind to ligands immobilised on the gold surface causing a change in the levels of the surface plasmon signals. Analysis of this change enables determination of both kinetic and analyte concentrations.

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