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Figure 2 | Respiratory Research

Figure 2

From: Down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis

Figure 2

Decreased ING4 expression in bleomycin (BLM)- induced pulmonary fibrosis (PF) following disease progression. (A) Representative immunohistochemistry with an anti-ING4 antibody on lung paraffin sections from BLM-treated mice (7, 15, and 23, days post-administration). ING4 was mainly expressed in alveolar epithelium (days 7 and 15) whereas showed weak staining within areas of dense fibrosis and collagen deposition at late disease stages (day 21). (B) Computerized image analysis of immunostained sections. *p < 0.05, **p < 0.005, ***p < 0.001. (One way ANOVA and unpaired t-test with Bonferroni correction, F = 71,126).

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Respiratory Research

ISSN: 1465-993X

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