Table 1 ADAMs/ADAMTS modulation in airway diseases.
From: Role of ADAM and ADAMTS metalloproteinases in airway diseases
ADAMs | Modulation | Type of airway disease | Type of study | Reference |
|---|---|---|---|---|
ADAM-8 | ↗ | asthma | human | |
↗ | asthma | mouse | ||
ADAM-9 | ↗ | asthma | human | [51] |
ADAM-10 | ↗ | asthma | mouse | [73] |
ADAM-12 | ↗ | asthma | human | [51] |
ADAM-17 | ↗ | asthma | mouse | [73] |
↗ | COPD | rat | [80] | |
ADAM-28 | ↗ | asthma | mouse | [73] |
ADAM33 | ↗ | asthma | human | |
SNP | COPD | human | ||
ADAMTS-1 | ↘ | asthma | human | [51] |
ADAMTS-12 | SNP | asthma | human | [84] |
ADAMTS-15 | ↘ | asthma | human | [51] |
↗ | asthma | mouse | [73] |