Antenatal and postnatal corticosteroid and resuscitation induced lung injury in preterm sheep

Respiratory Research

Table 2 Markers of Lung and Systemic Injury and Inflammation

Group	N	BAL Protein (mg/kg)	Injury Score (0 ut of 8)	BAL Neutrophils/kg ×10⁶	Liver SAA3 mRNA¹
Unventilated Controls	8	25 ± 12	1.5 ± 0.6	0.1 ± 0.3	1.0 ± 0.05
Injury	8	107 ± 24*	5.0 ± 0.9*	23.0 ± 14.9*	3.8 ± 1.4*
Injury + Beta	8	60 ± 16* ^t	3.4 ± 1.0* ^t	14.5 ± 17.7*	5.4 ± 1.9*
Injury + Dex	8	119 ± 32*	3.5 ± 1.0* ^t	22.0 ± 10.9*	7.2 ± 1.8*
Injury + Cortisol	5	97 ± 21*	4.7 ± 0.8*	17.3 ± 11.3*	7.2 ± 1.5*

*p < 0.05 vs Controls, ^t p < 0.05 vs Injury. BAL is bronchoalveolar lavage. SAA3 is serum amyloid A3. 1. expressed relative to a relative value of 1 for unventilated controls.

ISSN: 1465-993X