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Figure 1 | Respiratory Research

Figure 1

From: PDGF-Rα gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts

Figure 1

The pattern of PDGF-Rα expression in mouse lung fibroblasts changes during alveolar development. Mouse lung fibroblasts were isolated from either wildtype (WT, A) or mice carrying the PDGF-Rα-GFP transgene (GFP, B and C). Expression of PDGF-Rα-GFP was compared at postnatal days 4 (P4, B) and 12 (P12, C). The average abundance of GFP-positive fibroblasts expressed as a percentage of total fibroblasts (cells adherent to plastic after 1 h), is summarized in the column graph (D). For P4, n = 5 groups of 2 to 4 mice, and at P12, n = 7 groups of 2 to 4 mice. For the FACS histograms, "counts" on the y-axis = the number of events, and on the x-axis, "GFP-A," = GFP Area. **, p < 0.001.

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Respiratory Research

ISSN: 1465-993X

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