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Figure 1 | Respiratory Research

Figure 1

From: Characterisation of the proximal airway squamous metaplasia induced by chronic tobacco smoke exposure in spontaneously hypertensive rats

Figure 1

Morphology of TS induced changes in proximal and distal airways of SH rats. H&E stain for pathological assessment. Morphological changes were seen in proximal (A-C) and distal airways (D-F) following TS exposure. FA exposed rats showed minimal changes to proximal (A) and distal (D) airways. Exposure to TS for 7 (B) and 14 (C) weeks induced a squamous metaplasia in proximal airways (see high power inset in panel C). Distal airways showed epithelial hypertrophy at 7 weeks (E) but progressed to squamous metaplasia in occasional airways by 14 weeks (F). Magnification bar in F applies to panels A, B, D-F.

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