Figure 5

Vascular endothelial growth factor (VEGF) and keratinocyte growth factor (KGF) effects on alveolar epithelial wound repair. Effect of addition of different combinations of bronchoalveolar lavage fluid (BALF), VEGF (10 pg/ml), and soluble VEGF-receptor 1 (sVEGFr1; 6 ng/ml) (A), or various concentrations of KGF (B) on in vitro alveolar epithelial wound healing. Bars represent mean wound closure + SEM (% of control) of triplicate experiments (*p < 0.05, and **p < 0.01 vs control). No significant differences are present between BALF alone and BALF with any addition. Significant differences between VEGF, and both sVEGFr1 and VEGF + sVEGFr1 are present (both p < .05).