| IL-1Ra | IL-2 | IL-6 | IL-8 | IP-10 | RANTES | MCP-1 | Eotaxin |
---|
Rapid COPD | 30.1(36.7) | 27.4(43.2) | 31.7(38.0) | 32.7(23.9) | 24.8(17.7) | 28.0(28.1) | 25.3(37.6) |
30.6(34.3)
|
Stable COPD | 9.0(22.3) | 13.6(37.0) | 20.6(38.2) | 18.0(25.4) | 15.8(17.6) | 22.6(38.0) | 8.3(23.4) |
5.9(13.2)
|
Normal Controls | 16.4(39.0) | 27.5(51.3) | 16.6(47.0) | 38.2(36.3) | 39.3(29.3) | 6.6(18.6) | 9.3(26.2) |
0(0)
|
- n = 9 for rapid decliners, n = 11 for stable COPD subjects, n = 8 for normal controls
- Data is reported as mean ± standard error of measurement
- The standard error of measurement is in parentheses
- Lung lavage levels of 25 human cytokines were measured in stable COPD participants (n = 11), rapidly progressive COPD participants (n = 9) and normal controls (n = 8) using the Luminex 25-plex assay. Eight of these cytokines had detectable levels within our samples. Significant changes in cytokine levels between stable and rapid decliners were detected for eotaxin-1 (indicated in bold, p < 0.05). Parentheses indicate standard error of measurement.