Table 6 Comparison of Plasma Cytokine Levels between Rapid Decliners Stable COPD Participants and Normal Controls.
From: Eosinophil and T cell markers predict functional decline in COPD patients
| Â | NORMALS (N = 11) | STABLE (N = 17) | DECLINERS (N = 10) | p value Stable vs. Rapid | p value Stable vs. Normals |
|---|---|---|---|---|---|
IL-1β | 151(55) | 414(104) | 184(61) | <0.06 | <0.03 |
IL-1Ra | 1665(589) | 3514(1078) | 1945(598) | NS | NS |
IL-2* | 28(12) | 62(11) | 25(7) | <0.04 | =0.10 |
IL-2R* | 511(162) | 700(128) | 495(97) | NS | NS |
IL-4 | 21(9) | 70(22) | 48(11) | NS | <0.04 |
IL-5 | 9(4) | 32(9) | 16(4) | NS | <0.03 |
IL-6 | 47(17) | 85(20) | 56(10) | NS | NS |
IL-7 | 37(16) | 101(25) | 97(13) | NS | <0.03 |
IL-8 | 10(2) | 20(4) | 15(2) | NS | <0.03 |
IL-10 | 78(52) | 51(17) | 40(16) | NS | NS |
IL-12p40/p70 | 503(53) | 592(117) | 586(58) | NS | NS |
IL-13 | 17(9) | 42(16) | 19(8) | NS | NS |
IL-15 | 101(48) | 203(51) | 117(20) | NS | NS |
IL-17 | 46(24) | 123(38) | 80(18) | NS | NS |
TNF-α | 69(22) | 88(28) | 53(12) | NS | NS |
IFN-α | 70(41) | 308(83) | 188(48) | NS | <0.02 |
IFN-γ | 73(32) | 187(50) | 109(22) | NS | <0.05 |
GM-CSF | 192(71) | 463(120) | 356(63) | NS | <0.05 |
MIP-1α | 119(19) | 206(36) | 168(30) | NS | <0.04 |
MIP-1β | 831(235) | 1976(431) | 1422(243) | NS | <0.03 |
IP-10 | 60(12) | 88(11) | 106(18) | NS | <0.05 |
MIG | 505(247) | 941(235) | 610(87) | NS | NS |
EOTAXIN* | 1043(237) | 572(128) | 834(164) | =0.11 | <0.04 |
RANTES | 30969(4420) | 30066(4135) | 39411(7420) | NS | NS |
MCP-1 | 1931(158) | 1771(181) | 1785(129) | NS | NS |