Impaired immune responses in the lungs of aged mice following influenza infection

Respiratory Research

Table 1 Symptom Score

Score Symptoms	0 each	1 each	2 each
Ruffled Fur	Absent	Present
Hunched Back	Absent	Present
Activity	Normal	Reduced	Severely Reduced

Mice were evaluated daily and scored for individual symptoms. Ruffled fur (absent = 0; present = 1), hunched back (absent = 0; present = 1) and activity (normal = 0; reduced = 1; severely reduced = 2) were evaluated. The final score was the addition of each individual symptom score (e.g. an animal showing ruffled fur (1), hunched back (1) and reduced activity (1) was scored as 3). The minimum score was 0 for a healthy mouse and 1-4 for illness, depending on severity.

ISSN: 1465-993X