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Figure 1 | Respiratory Research

Figure 1

From: Nitric oxide synthases in infants and children with pulmonary hypertension and congenital heart disease

Figure 1

Lungs from infants with pulmonary hypertension (A, C, E) and from control patients of similar age (B, D, F) stained for (A and B) eNOS, (C and D) iNOS, (E and F) nNOS. (A) Cardiac patient small pulmonary artery showing mild endothelial positivity for eNOS. Intra-alveolar macrophages and alveolar lining cells also positive with very mild positivity also noted in media. (B) Small pulmonary artery from control patient showing very mild endothelial positivity for eNOS. (C) Cardiac patient small pulmonary artery showing iNOS positivity in endothelium and media. Intra-alveolar macrophages stained also strongly positive. (D) Small pulmonary artery of control patient showing no significant iNOS positivity. Intra-alveolar macrophages were positive. (E) Cardiac patient small pulmonary artery showing no immunocytochemical positivity for nNOS. (F) Control patient small pulmonary artery showing no positivity by immunocytochemistry for nNOS. × 400.

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