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Table 2 Univariate and multivariate linear mixed model (LMM) analysis evaluating lung function parameters as explanatory variables of PaO2, including adjustment by "year at testing"

From: Long-term gas exchange characteristics as markers of deterioration in patients with cystic fibrosis

 

LMM univariate analysis adjusted for age and test year

 

Coefficient

95 % CI

p

FRCpleth(SDS)

-1.641

-1.907 to -1.376

< 0.0001

LCI (SDS)

-0.338

-0.403 to -0.272

< 0.0001

VTG (SDS)

-1.209

-1.471 to -0.947

< 0.0001

sReff (SDS)

-0.517

-0.599 to -0.434

< 0.0001

FEV1 (SDS)

1.126

0.991 to 1.261

< 0.0001

FEF50 (SDS)

0.586

0.507 to 0.664

< 0.0001

BMI (SDS)

1.374

0.922 to 1.825

< 0.0001

 

LMM multivariate analysis with backward elimination procedure*

 

Coefficient

95 % CI

p

FRCpleth(SDS)

-0.868

-1.180 to -0.5555

< 0.0001

LCI (SDS)

-0.125

-0.191 to -0.058

< 0.0001

sReff (SDS)

-0.123

-0.225 to -0.021

0.019

FEV1 (SDS)

0.511

0.284 to 0.738

< 0.0001

FEF50 (SDS)

0.161

0.0412 to 0.281

0.008

  1. * VTG and BMI excluded from model