Figure 2
Development of heavy P. murina infection in immunosuppressed Wild-Type (WT) and SP-A deficient (KO) mice. WT (open square) and KO (black triangle) mice were immunosuppressed for 4 weeks, sacrificed and P. murina cysts forms in the lungs were quantitated microscopically. The limit of P. murina detection is approximately 2.5 × 104 cyst forms/lung (log10 4.4). Data were expressed as log10 cysts per mouse. Horizontal lines indicate mean log cysts per group. Each point represents a single mouse. *p < 0.01 as determined by t test. The arrow indicates the level of detection of microscopic enumeration.