Figure 4From: Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblastsEffects of curcumin and a cathepsin inhibitor on wound healing in HFL-1 cell scratch model. Representative images of wound healing assay (A) and its quantification (B) demonstrate the dose-dependent reduction of wound closure rates by curcumin. In contrast, LHVS, a pan-cathepsin inhibitor significantly increased wound closure rates (C). All data represent means of three independent experiments ± SD (* p < 0.05, all compared to bleomycin treated group only).Back to article page